Palù takes stock of hepatitis in children, Omicron, vaccines: how they are born and how long they will last

From the ongoing alarm for acute hepatitis in children. Passing through the danger of the Omicron sub-variants. Until the need for updated vaccines for all, Giorgio Palù, Emeritus Professor of Virology at the University of Padua, President ofAifa and former member of the CTS, he answers the most frequently asked questions at the moment. Based on two important considerations, which the expert leaves to an interview with The printout, both in relation to hepatitis in children. What about the Sars-Cov-2 epidemic in its insidious mutations.

Palù makes status of hepatitis in children, Omicron, vaccines

The first: the liver disease affecting the little ones, “has so far not had the spread feared, although it has mainly affected children under the age of 5 who have not been vaccinated against Sars-Cov-2. The most likely cause is human adenovirus F41, which is already associated with gastrointestinal formsWhile on Covid, he assumes: “He will stay with us for a long time with a seasonal trend. Until October, the situation on our hemisphere should remain relatively good with reduced incidence of cases and low pressure on welfare benefits. Since it is caused “of an airborne virus, it will return and worry us. The only data that remains alarming are the dead, because it is as if a plane crashed every day.”

Palù: hepatitis, Omicron and vaccines: “We need updated doses and increasingly effective drugs”

It follows, Palù continues in his discussion, that “we must have faith in current vaccines. Which still protect very well against serious disease. And hopes for research to produce updated doses and increasingly effective drugs for the fallNot only. The expert who takes stock of the interview with Torino on a daily basis examines the new data from the Higher Institute of Health at 397,000 reinfections with Sars-Cov-2 since the end of Augustcontextualisation of these genes to demonstrate “yet another proof that it does not make sense to talk about herd immunity. To do this – the professor answers – it would require a stable virus and a vaccine that totally covers. It should be noted, however, that the virus is becoming more and more endemic and that around 90% of infections, including the unvaccinated and re-infected, are asymptomatic“.

“We will have to look for a polyvalent vaccine against all coronaviruses”

So is vaccination still necessary? “Of course, the usefulness of the fourth dose is unfortunately underestimated both in Italy and in other countries like Germany,” he adds. And Will we all make it to the fall?Ema reminded that for the whole population it is necessary to focus on vaccines updated to the circulating variants and sub-variants Palù notes. Besides to seek in the long term a polyvalent vaccine against all coronavirus. Once the first ones have been approved – they will probably be evaluated in September – they can be done.

“Omicron could vary in a very different and more pathogenic variant”

So why is Omicron producing so many sub-variants? “That Sars-Cov-2 varies continuously randomly. It can occur in immunosuppressed individuals, where the infection lasts longer, or it can occur by recombination with an exchange of genes between two viruses that infect the same human or animal cell – observes the scientist -. We have already seen the case of the human-animal-human passage with bats and mink. But it can also happen with other species such as hamsters and ferrets“. It still is.” We can not rule it out Omicron mutates to a very different and more pathogenic variantbut it would be a process contrary to evolutionary fate viruses that have so far lost virulence no longer infect the lungs“.

Palù: “Sars-Cov-2 will stay with us for a long time with a seasonal trend”

So how does Palù see the development of the pandemic between now and Christmas? “Sars-Cov-2 will stay with us for a long time with a seasonal trend the expert speculates,. The situation was supposed to remain relatively good on our hemisphere until October. With reduced incidence of cases and low pressure on welfare benefits. Also, is Covid-19 caused by an airborne virus, it will worry us again. The only fact that remains alarming is that of the dead: because it is as if a plane crashed every day “…

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